The Mediterranean province includes the communities of several countries around the Mediterranean coast: Spain, Tunisia, Egypt, Israel, Turkey, Southern France and a few Sisters in Rome. Several languages are spoken: French, English, Arabic, Hebrew and Spanish.

ISRAEL: Already on August 7, 1855, Father M. Alphonse Ratisbonne had the opportunity of travelling to Jerusalem "full of zeal and hope." Above all, he wanted to found something in the Holy Land, where a few Sisters joined him in April 1856. He bought land in 1857, built the complex that is called "Ecce Homo", and then also set up in the village of Ein Karem. In 1860, all kinds of children were welcomed in the two houses.

TURKEY: During that same period, in September 1856, twelve Sisters had already been sent to "Constantinople", where they immediately took over a school which until then had been directed by the Sisters of Charity. The Fathers Ratisbonne were very aware of how important it was to be present in the capital of the Ottoman Empire: possible future administrative relations could be facilitated as a result; on the other hand, these first steps towards the Middle East were entirely in line with their ideal: to gather together children who were different from one another because of their religion, their culture or their nationality, and to educate them to a way of life that was without a prioris, without prejudices. Another house was founded in Smyrna (Izmir); it was closed in 1922 as a result of the fire which ravaged the city.

EGYPT: After Istanbul and Jerusalem, the beautiful boarding school in Ramleh-Alexandria, Egypt was opened in 1880; it escaped the fire of 1882, thanks to the presence of the English staff headquarters within its wall, which was headed by the Duke of Connaught, the Queen's son. This exceptional boarding school, of which many former pupils remain extraordinarily faithful to Sion, was handed over to Coptic Sisters during the 1970's.

TUNISIA: Founded in 1881, the houses of Tunis and then of Khaznadar educated young Jewish, Muslim and Christian girls for a hundred years, thus contributing towards the development of the country, above all of women, and towards understanding between the faithful of various religions.

ROME: For several years now, Sisters from the Mediterranean province have been sent to Rome, at the service of the Generalate in activities both in the house and outside.

SPAIN: These foundations in a country that is marked by its Jewish and Muslim roots, and which is now rediscovering the wealth of these roots, are more recent. Madrid was founded in 1958 and from the beginning had as its aim dialogue between Jews and Christians. The foundation in Barcelona was made in 1967, and its original aim was more for social development; this community was closed in 1989.

Finally, the Congregation set up two Residences for elderly Sisters in the good air of Provence, one near Marseille, the other near Grasse.